منابع مشابه
Partial Cloning and Nucleotide Sequencing of Glutamate Decarboxylase Gene Isoform 65 from Human Brain
Background: Gamma -aminobutyric acid (GABA), a non-protein amino acid acts as an inhibitory neurotransmitter in the central nervous system of mammalians. The glutamate decarboxylase (GAD) is responsible for the conversion of L-glutamate to GABA. The human brain has two isoforms of this enzyme, GAD65 and GAD67 that differ in molecular weight, amino acid sequence, antigenicity, cellular location ...
متن کاملCloning and characterization of a third human lysyl hydroxylase isoform.
Lysyl hydroxylase (EC 1.14.11.4), a homodimer, catalyzes the formation of hydroxylysine in collagens. Recently, an isoenzyme termed lysyl hydroxylase 2 has been cloned from human sources [M. Valtavaara, H. Papponen, A.-M. Pirttilä, K. Hiltunen, H. Helander and R. Myllylä (1997) J. Biol. Chem. 272, 6831-6834]. We report here on the cloning of a third human lysyl hydroxylase isoenzyme, termed lys...
متن کاملCloning of a rat-specific long PCP4/PEP19 isoform.
We report the identification of a cDNA that encodes a putative protein of 94 amino acids and expected molecular weight of 10.7 kDa, the C-terminal half of which is identical to that of PEP19, a small, brain-specific protein involved in Ca++/calmodulin signaling. The novel rat-specific protein, tentatively named long PEP19 isoform (LPI), is the product of alternative splicing of the rat PCP4 gen...
متن کاملpartial cloning and nucleotide sequencing of glutamate decarboxylase gene isoform 65 from human brain
background: gamma -aminobutyric acid (gaba), a non-protein amino acid acts as an inhibitory neurotransmitter in the central nervous system of mammalians. the glutamate decarboxylase (gad) is responsible for the conversion of l-glutamate to gaba. the human brain has two isoforms of this enzyme, gad65 and gad67 that differ in molecular weight, amino acid sequence, antigenicity, cellular location ...
متن کاملToll-like Receptor 3 (TLR3) Induces Apoptosis via Death Receptors and Mitochondria by Up-regulating the Transactivating p63 Isoform (TAP63 )*
Ruili Sun, Yu Zhang, Qingshan Lv , Bei Liu**, Miao Jin, Weijia Zhang, Qing He, Minjie Deng, Xueting Liu, Guancheng Li, Yuehui Li, Guohua Zhou, Pingli Xie, Xiumei Xie , Jinyue Hu, and Zhaojun Duan From the Central Laboratory, Renmin Hospital, Wuhan University, Wuhan 430060, the Cancer Research Institute, Central South University, Changsha 410078, the Department of Laboratory Medicine, XinXiang M...
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ژورنال
عنوان ژورنال: Yonsei Medical Journal
سال: 2004
ISSN: 0513-5796
DOI: 10.3349/ymj.2004.45.2.359